Identification of Biomarkers for Non–small-cell Lung Cancer Patients Treated With an Immune Checkpoint Inhibitor

…, K Somekawa, M Hirata, C Kamimaki… - Anticancer …, 2020 - ar.iiarjournals.org
Background/Aim: Immune checkpoint inhibitors (ICIs) have an important role in lung cancer
therapy. Although the programmed cell death protein-1 (PD-L1) tumor proportion score (TPS…

Whole-genome sequencing predicting phenotypic antitubercular drug resistance: meta-analysis

…, A Kaneko, K Somekawa, C Kamimaki… - The Journal of …, 2023 - academic.oup.com
Background For simultaneous prediction of phenotypic drug susceptibility test (pDST) for
multiple antituberculosis drugs, the whole genome sequencing (WGS) data can be analyzed …

Identification of a novel biomarker based on lymphocyte count, albumin level, and TBAg/PHA ratio for differentiation between active and latent tuberculosis infection in …

S Katakura, N Kobayashi, H Hashimoto, C Kamimaki… - Tuberculosis, 2020 - Elsevier
Data from China have shown that the ratio of Mycobacterium tuberculosis-specific antigen (TBAg)
spots obtained from the T-SPOT.TB test to the number of positive control …

MicroRNA‐200b is a potential biomarker of the expression of PD‐L1 in patients with lung cancer

…, N Kobayashi, H Hashimoto, C Kamimaki… - Thoracic …, 2020 - Wiley Online Library
Background Advanced non‐small cell lung cancer (NSCLC) has a high mortality rate and
poor prognosis. However, outcomes have gradually improved after the introduction of novel …

Pembrolizumab monotherapy versus pembrolizumab plus chemotherapy in patients with non‐small‐cell lung cancer: A multicenter retrospective trial

…, N Fukuda, A Kaneko, C Kamimaki… - Thoracic …, 2022 - Wiley Online Library
Background Pembrolizumab alone or in combination with chemotherapy is a standard
treatment for patients with non‐small‐cell lung cancer (NSCLC) with high programmed death‐…

Resistance mechanisms of epidermal growth factor receptor tyrosine kinase inhibitors in non‐small cell lung cancer patients: A meta‐analysis

N Kobayashi, S Katakura, C Kamimaki… - Thoracic …, 2021 - Wiley Online Library
Background Differences in the resistance mechanisms of epidermal growth factor receptor
tyrosine kinase inhibitors in patients with non‐small cell lung cancer (NSCLC) harboring …

Adverse events induced by durvalumab and tremelimumab combination regimens: a systematic review and meta-analysis

…, N Fukuda, A Izawa, C Kamimaki… - Therapeutic …, 2023 - journals.sagepub.com
Background: Immune checkpoint inhibitors (ICIs) have shown remarkable therapeutic outcomes
among cancer patients. Durvalumab plus tremelimumab (DT) is under investigation as a …

[HTML][HTML] Regional differences in epidermal growth factor receptor-tyrosine kinase inhibitor therapy in lung cancer treatment using a national database in Japan

…, A Goto, A Kaneko, N Fukuda, C Kamimaki… - Scientific Reports, 2023 - nature.com
Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) are extensively
used in the treatment of non-small cell lung cancer (NSCLC); hence, equal access to them is …

T‐cell response to phytohemagglutinin in the interferon‐γ release assay as a potential biomarker for the response to immune checkpoint inhibitors in patients with non …

C Kamimaki, N Kobayashi, M Hirata… - Thoracic …, 2021 - Wiley Online Library
Background Immune checkpoint inhibitors are a standard treatment for advanced lung cancer,
although it remains important to identify biomarkers that can accurately predict treatment …

Class A CpG oligodeoxynucleotide inhibits IFN‐γ‐induced signaling and apoptosis in lung cancer

…, N Kobayashi, S Katakura, C Kamimaki… - Thoracic …, 2020 - Wiley Online Library
Background Currently, anticancer immunotherapy based on PD‐1/PD‐L1 blockade with
immune checkpoint inhibitors (ICIs) is being used as a standard therapy for non‐small cell lung …