Extracellular matrix remodeling in idiopathic pulmonary fibrosis. It is the 'bed'that counts and not 'the sleepers'

IP Tomos, A Tzouvelekis, V Aidinis… - Expert review of …, 2017 - Taylor & Francis
Introduction: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive interstitial lung
disease characterized by irreversible fibrosis. Current disease pathogenesis assumes an …

Histone deacetylase inhibitors as a novel targeted therapy against non-small cell lung cancer: where are we now and what should we expect?

C Damaskos, I Tomos, N Garmpis… - Anticancer …, 2018 - ar.iiarjournals.org
Non-small cell lung cancer constitutes the most common type of lung cancer, accounting for
85-90% of lung cancer, and is a leading cause of cancer-related death. Despite the progress …

High levels of IL-6 and IL-8 characterize early-on idiopathic pulmonary fibrosis acute exacerbations

SA Papiris, IP Tomos, A Karakatsani, A Spathis… - Cytokine, 2018 - Elsevier
Introduction Controversy exists about the pathogenesis of idiopathic pulmonary fibrosis acute
exacerbations (IPF-AEs). According to one hypothesis IPF-AEs represent the development …

[HTML][HTML] Molecular and Genetic Biomarkers in Idiopathic Pulmonary Fibrosis: Where Are We Now?

I Tomos, I Roussis, AM Matthaiou, K Dimakou - Biomedicines, 2023 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) represents a chronic progressive fibrotic interstitial lung
disease of unknown cause with an ominous prognosis. It remains an unprecedent clinical …

[HTML][HTML] Long-term personal air pollution exposure and risk for acute exacerbation of idiopathic pulmonary fibrosis

I Tomos, K Dimakopoulou, ED Manali, SA Papiris… - Environmental …, 2021 - Springer
Background Urban air pollution is involved in the progress of idiopathic pulmonary fibrosis (IPF).
Its potential role on the devastating event of Acute Exacerbation of IPF (AE-IPF) needs …

[HTML][HTML] Post-COVID-19 interstitial lung disease: Insights from a machine learning radiographic model

…, IC Papanikolaou, E Bibaki, I Tomos… - Frontiers in …, 2023 - frontiersin.org
Introduction Post-acute sequelae of COVID-19 seem to be an emerging global crisis.
Machine learning radiographic models have great potential for meticulous evaluation of post-…

Lung cancer in patients with idiopathic pulmonary fibrosis. A retrospective multicenter study in Greece

…, E Bouros, V Tzilas, E Manali, I Tomos… - Pulmonary …, 2020 - Elsevier
Background Abundant evidence supports an association between Idiopathic Pulmonary
Fibrosis (IPF) and lung cancer development. Data on diagnosis and management of patients …

[HTML][HTML] COVID-19 in patients with pulmonary alveolar proteinosis: a European multicentre study

…, CR Cordeiro, EM Antonogiannaki, IP Tomos… - ERJ open …, 2023 - Eur Respiratory Soc
Granulocyte–macrophage colony-stimulating factor (GM-CSF) signalling is essential in both
alveolar macrophage (AM) differentiation and activation of lung immune cells [1]. …

[HTML][HTML] The impact of COVID-19 pandemic on surgical treatment of resectable non-small cell lung cancer in Greece

I Tomos, EI Kapetanakis, K Dimakopoulou, T Raptakis… - Life, 2023 - mdpi.com
Background: The coronavirus disease (COVID-19) pandemic has posed an unprecedented
challenge to health systems, and has significantly affected the healthcare of lung cancer …

Early COVID-19 lockdown in Greece and idiopathic pulmonary fibrosis: a beneficial “impact” beyond any expectation

…, A Xyfteri, A Haritou, I Korbila, IP Tomos… - European …, 2021 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF) is an irreversibly progressive diffuse lung disease
characterised by a usual interstitial pneumonia (UIP) pattern. IPF presents with an ominous …