User profiles for Lydia J. Finney
Lydia FinneySenior Clinical Lecturer, Imperial College London Verified email at imperial.ac.uk Cited by 1089 |
[HTML][HTML] Inhaled corticosteroids downregulate the SARS-CoV-2 receptor ACE2 in COPD through suppression of type I interferon
… Author links open overlay panel Lydia J. Finney PhD a , Nicholas Glanville PhD b , Hugo
Farne PhD a , Julia Aniscenko a , Peter Fenwick PhD a , Samuel V. Kemp MD a c , Maria-Belen …
Farne PhD a , Julia Aniscenko a , Peter Fenwick PhD a , Samuel V. Kemp MD a c , Maria-Belen …
[HTML][HTML] Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations
…, RP Walton, LJ Finney, J Aniscenko, J Zhu… - Nature …, 2018 - nature.com
Inhaled corticosteroids (ICS) have limited efficacy in reducing chronic obstructive pulmonary
disease (COPD) exacerbations and increase pneumonia risk, through unknown …
disease (COPD) exacerbations and increase pneumonia risk, through unknown …
[HTML][HTML] Airway mucins promote immunopathology in virus-exacerbated chronic obstructive pulmonary disease
…, G Radicioni, MT Cross, LJ Finney… - The Journal of …, 2022 - Am Soc Clin Investig
The respiratory tract surface is protected from inhaled pathogens by a secreted layer of mucus
rich in mucin glycoproteins. Abnormal mucus accumulation is a cardinal feature of chronic …
rich in mucin glycoproteins. Abnormal mucus accumulation is a cardinal feature of chronic …
Lower airway colonization and inflammatory response in COPD: a focus on Haemophilus influenzae
Bacterial infection of the lower respiratory tract in chronic obstructive pulmonary disease (COPD)
patients is common both in stable patients and during acute exacerbations. The most …
patients is common both in stable patients and during acute exacerbations. The most …
Inhaled corticosteroid suppression of cathelicidin drives dysbiosis and bacterial infection in chronic obstructive pulmonary disease
Bacterial infection commonly complicates inflammatory airway diseases such as chronic
obstructive pulmonary disease (COPD). The mechanisms of increased infection susceptibility …
obstructive pulmonary disease (COPD). The mechanisms of increased infection susceptibility …
Chronic obstructive pulmonary disease in sub-Saharan Africa: a systematic review
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a major global health
problem. Although COPD is the sixth most common cause of mortality in low- and middle-…
problem. Although COPD is the sixth most common cause of mortality in low- and middle-…
Antiviral immunity is impaired in COPD patients with frequent exacerbations
…, SL Loo, M Calderazzo, LJ Finney… - … of Physiology-Lung …, 2019 - journals.physiology.org
Patients with frequent exacerbations represent a chronic obstructive pulmonary disease (COPD)
subgroup requiring better treatment options. The aim of this study was to determine the …
subgroup requiring better treatment options. The aim of this study was to determine the …
Human rhinovirus impairs the innate immune response to bacteria in alveolar macrophages in chronic obstructive pulmonary disease
LJ Finney, KBR Belchamber, PS Fenwick… - American Journal of …, 2019 - atsjournals.org
… Correspondence and requests for reprints should be addressed to Lydia J. Finney, MBBCh.,
B.Sc., COPD Research Group, National Heart and Lung Institute, Imperial College, …
B.Sc., COPD Research Group, National Heart and Lung Institute, Imperial College, …
A double-blind, randomized, placebo-controlled trial of long-term doxycycline therapy on exacerbation rate in patients with stable chronic obstructive pulmonary …
Rationale: Chronic obstructive pulmonary disease (COPD) exacerbations are a major
cause of morbidity and mortality, and preventing them is a key treatment target. Long-term …
cause of morbidity and mortality, and preventing them is a key treatment target. Long-term …
Repurposing existing drugs for the treatment of COVID-19
The rapid global spread and significant mortality associated with the coronavirus disease (COVID-19)
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral …
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral …