Background Mitoxantrone plus prednisone reduces pain and improves the quality of life in
men with advanced, hormone-refractory prostate cancer, but it does not improve survival. We …

Background Ventricular arrhythmia and sudden cardiac death late after repair of tetralogy of
Fallot are devastating complications in adult survivors of early surgery, but their prediction …

Gliomas are primary brain tumours that are thought to derive from neuroglial stem or
progenitor cells. On the basis of their histological appearance, they have been traditionally …

Rationale: The Third National Health and Nutrition Examination Survey (NHANES III) reference
is currently recommended for interpreting spirometry results, but it is limited by the lack of …

Purpose A randomized, phase III, placebo-controlled, partially blinded clinical trial (REGAL [Recentin
in Glioblastoma Alone and With Lomustine]) was conducted to determine the …

Purpose Reports have suggested that metastatic site is an important predictor of overall
survival (OS) in men with metastatic castration-resistant prostate cancer (mCRPC), but these …

Background Docetaxel plus prednisone is standard first-line chemotherapy for men with
metastatic castrate-resistant prostate cancer. Aflibercept is a recombinant human fusion protein …

Treatment of Alzheimer’s disease (AD) is difficult due to ignorance of its pathogenesis. AD
patients have defects in phagocytosis of amyloid-β (1-42)(Aβ) in vitro by the innate immune …

OBJECTIVE In light of increased fatality from acute events and the increased frequency of
chronic complications, life expectancy might well be shortened in older patients with diabetes. …

We have tested a hypothesis that the natural product curcuminoids, which has epidemiologic
and experimental rationale for use in AD, may improve the innate immune system and …