User profiles for Tiago M. Alfaro
Tiago M AlfaroUniversity of Coimbra Verified email at fmed.uc.pt Cited by 832 |
Co‐localization and functional interaction between adenosine A2A and metabotropic group 5 receptors in glutamatergic nerve terminals of the rat striatum
The anti‐Parkinsonian effect of glutamate metabotropic group 5 (mGluR5) and adenosine A
2A receptor antagonists is believed to result from their ability to postsynaptically control the …
2A receptor antagonists is believed to result from their ability to postsynaptically control the …
[HTML][HTML] Epidemiology of interstitial lung diseases and their progressive-fibrosing behaviour in six European countries
…, H Fretheim, S Neves, TM Alfaro… - ERJ open …, 2022 - Eur Respiratory Soc
The PERSEIDS study aimed to estimate incidence/prevalence of interstitial lung diseases (ILDs),
fibrosing interstitial lung diseases (F-ILDs), idiopathic pulmonary fibrosis (IPF), systemic …
fibrosing interstitial lung diseases (F-ILDs), idiopathic pulmonary fibrosis (IPF), systemic …
Neuronal adenosine A2A receptors are critical mediators of neurodegeneration triggered by convulsions
Neurodegeneration is a process transversal to neuropsychiatric diseases and the understanding
of its mechanisms should allow devising strategies to prevent this irreversible step in …
of its mechanisms should allow devising strategies to prevent this irreversible step in …
Chronic coffee consumption and respiratory disease: A systematic review
Purpose The widespread consumption of coffee means that any biological effects from its
use can lead to significant public health consequences. Chronic pulmonary diseases are …
use can lead to significant public health consequences. Chronic pulmonary diseases are …
[HTML][HTML] Educational aspects of rare and orphan lung diseases
People with rare lung diseases often suffer the burden of delayed diagnosis, limited treatment
options, and difficulties in finding expert physicians. One of the reasons for the delay in …
options, and difficulties in finding expert physicians. One of the reasons for the delay in …
Comorbidity in idiopathic pulmonary fibrosis-what can biomarkers tell us?
TM Alfaro, C Robalo Cordeiro - Therapeutic Advances in …, 2020 - journals.sagepub.com
Idiopathic pulmonary fibrosis (IPF) is characterized by progressive parenchymal scarring,
leading to dyspnoea, respiratory failure and premature death. Although IPF is confined to the …
leading to dyspnoea, respiratory failure and premature death. Although IPF is confined to the …
[HTML][HTML] Managing granulomatous–lymphocytic interstitial lung disease in common variable immunodeficiency disorders: e-GLILDnet international clinicians survey
AAJM van de Ven, TM Alfaro, A Robinson… - Frontiers in …, 2020 - frontiersin.org
Background Granulomatous–lymphocytic interstitial lung disease (GLILD) is a rare, potentially
severe pulmonary complication of common variable immunodeficiency disorders (CVID). …
severe pulmonary complication of common variable immunodeficiency disorders (CVID). …
[HTML][HTML] Diagnosis of Fibrotic Hypersensitivity Pneumonitis: Is There a Role for Biomarkers?
JO Pereira, V Fernandes, TM Alfaro, S Freitas… - Life, 2023 - mdpi.com
Hypersensitivity pneumonitis is a complex interstitial lung syndrome and is associated with
significant morbimortality, particularly for fibrotic disease. This condition is characterized by …
significant morbimortality, particularly for fibrotic disease. This condition is characterized by …
Adenosine A2A receptors are up-regulated and control the activation of human alveolar macrophages
Chronic inflammatory lung diseases remain a health concern and new anti-inflammatory
treatments are needed. Targeting adenosine A 2A receptors (A 2A R) affords robust anti-…
treatments are needed. Targeting adenosine A 2A receptors (A 2A R) affords robust anti-…
Effect of free radicals on adenosine A2A and dopamine D2 receptors in the striatum of young adult and aged rats
Parkinson’s disease (PD) is a prevalent age-related motor dysfunction resulting from the
hyperactivity of the indirect striatal pathway, which is controlled in an antagonistic manner by …
hyperactivity of the indirect striatal pathway, which is controlled in an antagonistic manner by …