User profiles for Y.I. Choi

Yi Sun Choi

Postdoctoral researcher, Yonsei University
Verified email at yonsei.ac.kr
Cited by 726

[HTML][HTML] Microfluidic device with brain extracellular matrix promotes structural and functional maturation of human brain organoids

…, Y An, J Kim, YS Choi, JS Lee, J Kim, WY Choi… - Nature …, 2021 - nature.com
Brain organoids derived from human pluripotent stem cells provide a highly valuable in vitro
model to recapitulate human brain development and neurological diseases. However, the …

[HTML][HTML] Tissue extracellular matrix hydrogels as alternatives to Matrigel for culturing gastrointestinal organoids

S Kim, S Min, YS Choi, SH Jo, JH Jung, K Han… - Nature …, 2022 - nature.com
Matrigel, a mouse tumor extracellular matrix protein mixture, is an indispensable component
of most organoid tissue culture. However, it has limited the utility of organoids for drug …

Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia

…, MS Huang, H Zheng, J Wang, X Zhao, Y Li, JE Choi… - Nature …, 2012 - nature.com
To identify common genetic variants that contribute to lung cancer susceptibility, we conducted
a multistage genome-wide association study of lung cancer in Asian women who never …

Fungal brain infection modelled in a human-neurovascular-unit-on-a-chip with a functional blood–brain barrier

…, J Shin, B Cui, K Yang, YS Choi, N Choi… - Nature biomedical …, 2021 - nature.com
The neurovascular unit, which consists of vascular cells surrounded by astrocytic end-feet
and neurons, controls cerebral blood flow and the permeability of the blood–brain barrier (BBB…

Telomere length and the risk of lung cancer

JS Jang, YY Choi, WK Lee, JE Choi, SI Cha… - Cancer …, 2008 - Wiley Online Library
Telomeres play a key role in the maintenance of chromosome integrity and stability. There is
growing evidence that short telomeres induce chromosome instability and thereby promote …

Effect of genetically modified poplars on soil microbial communities during the phytoremediation of waste mine tailings

…, Y Kim, HR Song, JM Kim, YI Choi, H Yi - Applied and …, 2011 - Am Soc Microbiol
The application of transgenic plants to clean up environmental pollution caused by the
wastes of heavy metal mining is a promising method for removing metal pollutants from soils. …

Analysis of heritability and shared heritability based on genome-wide association studies for 13 cancer types

…, MD Chirlaque, JE Choi, YY Choi… - Journal of the …, 2015 - academic.oup.com
Background: Studies of related individuals have consistently demonstrated notable familial
aggregation of cancer. We aim to estimate the heritability and genetic correlation attributable …

[PDF][PDF] Neuromuscular electrical and thermal-tactile stimulation for dysphagia caused by stroke: a randomized controlled trial.

KB Lim, HJ Lee, SS Lim, YI Choi - Journal of …, 2009 - medicaljournalssweden.se
OBJECTIVE: The aim of this study was to assess the effectiveness of neuromuscular electrical
stimulation in patients with dysphagia caused by stroke. METHODS: Thirty-six subjects …

Transgenic poplar trees expressing yeast cadmium factor 1 exhibit the characteristics necessary for the phytoremediation of mine tailing soil

D Shim, S Kim, YI Choi, WY Song, J Park, ES Youk… - Chemosphere, 2013 - Elsevier
Genetic engineering of plants for phytoremediation is thought to be possible based on results
using model plants expressing genes involved in heavy metal resistance, which improve …

HDAC 6 regulates cellular viral RNA sensing by deacetylation of RIG‐I

…, TH Kim, WK Lee, DJ Jang, JE Yoon, YI Choi… - The EMBO …, 2016 - embopress.org
RIG ‐I is a key cytosolic sensor that detects RNA viruses through its C‐terminal region and
activates the production of antiviral interferons ( IFN s) and proinflammatory cytokines. While …