Immunosafety analysis of pharmaceutical surfactants is an important step in understanding
the complex mechanisms by which they induce side effects in susceptible patients. This …

Hypersensitivity reactions to liposomal drugs, often observed with Doxil and AmBisome, can
arise from activation of the complement (C) system by phospholipid bilayers. To understand …

Endothelial cells play a critical role in inflammation by responding to several endogenous
and exogenous proinflammatory stimuli. The three most studied factors that provide …

Educational aims To introduce the standardised method for sputum induction To provide a
guide for sputum processing To highlight important methodological aspects that may …

BACKGROUND: Reports in the recent experimental literature have provided contradicting
results in different animal species regarding the efficacy of IV lipid emulsion (ILE) in the …

To explore the role of complement (C) activation in the hypersensitivity reactions (HSRs) to
some anticancer drugs, as well as the use of the C activation biomarkers (C biom ) C3a, C5a …

Context: Vascular endothelial growth factor (VEGF) plays a role in asthma and pathological
pregnancies. Objective: This is the first study assessing plasma and exhaled breath …

Background The alternative pathway of the complement system is known to play a role in the
generation of asthmatic airway inflammation, but its regulatory complement protein, factor H …

The actions of ovariectomy on nitric oxide synthase (assessed by the citrullin assay), mucus
secretion (assessed by the Alcyan blue technique) and ulcerogenic response (indomethacin …

Complement (C) activation-related hypersensitivity reactions (HSRs) represent an unsolved
adverse immune effect of many iv administered “nanomedicines”, such as liposomal …